Gout

Epidemiology


Etiology

Risk factors


Pathophysiology

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Clinical features


Diagnostics


Treatment

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Tip

  • NSAIDs (e.g., naproxen, indomethacin) preferred if no contraindications
  • Colchicine used as second-line therapy

Acute gout flare

NSAIDs

Colchicine

Tip

Colchicine is unlikely to be effective when initiated > 24–36 hours after symptom onset. Colchicine is preferable in patients who cannot tolerate NSAIDs or systemic glucocorticoids (e.g., patients with PUD)

Chronic gout

Uricosurics