Approach to headaches

MigraineClusterTension
Sex predilectionFemale > maleMale > femaleFemale > male
Family historyOften present±None
OnsetVariableDuring sleep or similar timing dailyUnder stress
LocationOften unilateralBehind one eyeBand-like pattern around the head (bilateral)
CharacterPulsatile & throbbingExcruciating, sharp & steadyDull, tight & persistent
Duration4-72 hr15-180 min30 min to months/years
Associated symptomsPhotophobia, phonophobia & nausea, ± auraIpsilateral autonomic symptoms: Ipsilateral sweating, facial flushing, nasal congestion, pupillary changes & lacrimationMuscle tenderness in the head, neck, or shoulders

Migraine

Cluster headache

  • Quickly developing (within minutes), short, recurring attacks that usually occur in a cyclical pattern (“cluster periods”)
    • Circadian Rhythm: Attacks often occur at the same time each day, frequently awakening the patient from sleep (especially 1-2 AM).
    • Circannual Rhythm: Headaches occur in “clusters” or series lasting weeks to months, followed by remission periods that can last for months or years.
    • Attacks are brief (15-180 minutes) but occur frequently during a cluster period (from once every other day to 8 times a day).
  • Alcohol is a potent trigger during a cluster period but not during remission.