Risk & Protective Factors

  • Key Risk Factors:
    • Single strongest predictor: Prior suicide attempt.
    • Demographics: Elderly white males (≥65 yo) (highest completion rate); Females attempt more frequently (poisoning/OD), Males complete more frequently (firearms/hanging).
    • Psychiatric conditions: Bipolar disorder (highest lifetime suicide risk), MDD, Schizophrenia, BPD, SUD.
    • Clinical symptoms: Hopelessness (strong subjective predictor), severe agitation, insomnia, command hallucinations.
    • Environmental: Access to firearms in the home.
  • Key Protective Factors:
    • Responsibility to family / young children at home.
    • Religious / moral beliefs prohibiting suicide.
    • Strong social support system and therapeutic alliance.
  • High-Yield Board Trap: “No-suicide contracts” do NOT decrease suicide rates and are never the correct answer on Step 2 CK. Use collaborative safety planning.

Clinical Evaluation

  • Ideation: Thoughts of wanting to die or killing oneself.
    • Passive SI: Wish to be dead / sleep and not wake up, without active plan or intent.
    • Active SI: Thoughts of taking specific action to end one’s life.
  • Plan: The specific method, mechanism, location, or timeline developed to carry out suicide.
  • Intent: The conscious commitment, desire, or decision to act on suicidal thoughts and carry out the lethal act.

Risk Stratification & Management

  • High / Imminent Risk (Active SI + Plan and/or Intent):
    • Place on constant 1:1 observation and secure the environment (remove sharps/ligatures).
    • Offer voluntary psychiatric admission.
    • If patient refuses admission: Initiate involuntary psychiatric hospitalization (emergency hold). c
    • Rule: Breach confidentiality immediately to ensure safety; family or surrogate consent is not required for an involuntary hold.
  • Moderate Risk (Active SI + Plan, but NO Intent / Strong Protective Factors):
    • Evaluate for Intensive Outpatient Program (IOP) or voluntary brief observation.
    • Perform lethal means counseling: Instruct family/caregivers to secure/remove firearms and lock up medications.
  • Low Risk (Passive SI, NO Plan, NO Intent):
    • Outpatient management with scheduled psychiatric/PCP follow-up within 24–72 hours.
    • Establish a collaborative safety plan and provide 24/7 crisis hotline information (988).

Evidence-Based Treatments

  • Lithium:
    • Proven to reduce suicide risk and all-cause mortality in Bipolar Disorder and unipolar MDD maintenance.
  • Clozapine:
    • Only antipsychotic FDA-approved specifically to decrease suicidal behavior in Schizophrenia and Schizoaffective Disorder.
  • Electroconvulsive Therapy (ECT):
    • Fastest and most effective intervention for acute, severe suicidality associated with:
      • Severe refractory major depression.
      • Psychotic depression or severe bipolar depression.
      • Refusal to eat/drink (life-threatening inanition) or severe catatonia.
      • Severe suicidality during pregnancy when medications are contraindicated or too slow.
  • Dialectical Behavior Therapy (DBT):
    • Best therapy to reduce recurrent self-harm and suicide attempts in Borderline Personality Disorder (BPD).

High-Yield Exam Pearls

  • Direct Inquiry: Asking directly about suicidal ideation does NOT plant ideas or increase suicide risk; it is the essential standard of care.
  • Minors:
    • Actively suicidal minors require immediate notification of parents/guardians.
    • Parental consent is not required to place an acutely suicidal minor on an emergency psychiatric hold.
  • Post-Discharge Window:
    • The first month after discharge from an inpatient psychiatric unit carries the highest risk for completed suicide; mandatory close outpatient follow-up is critical.