Prostate

• Zonal Anatomy (Clinical Relevance)
  • Peripheral Zone:
    • Largest zone, located posteriorly.
    • Most common site (70-80%) of prostate carcinoma.
    • Palpable during a DRE.
    • Cancer here typically does not cause urinary symptoms until advanced.
  • Transitional Zone:
    • Surrounds the prostatic urethra.
    • Site of Benign Prostatic Hyperplasia (BPH).
    • BPH compresses the urethra, leading to lower urinary tract symptoms (LUTS) like hesitancy, weak stream, and nocturia.
  • Central Zone:
    • Surrounds the ejaculatory ducts.
    • Less common site for tumors.