• Encapsulated, lancet-shaped diplococci
  • Virulence factors and resistances
    • Capsular polysaccharides
    • IgA1 protease
  • Treatment
    • Penicillin and amoxicillin are traditionally used, but resistance is increasingly common due to altered penicillin-binding proteins (PBPs).
    • For severe infections (like meningitis or inpatient pneumonia), ceftriaxone is often used.
    • In cases of high resistance, vancomycin is an alternative.