Ectoparasites

Ectoparasiticides

• Drug
  • Permethrin
    • Blocks the deactivation of Na⁺ channels → uncontrollable depolarization of neuronal membranes → seizures and ultimately paralysis and death of the parasite
  • Malathion
    • Irreversible acetylcholinesterase inhibitor
• Indications
  • Pediculosis capitis
  • Pediculosis pubis
  • Scabies
• Applications
  • Topical application (in severe/recalcitrant cases: PLUS ivermectin PO)