• Primary Function: Main parasympathetic (“rest and digest”) innervation to thorax and abdomen up to the splenic flexure.
  • Key Anatomy:
    • Exits skull via jugular foramen.
    • Brainstem Nuclei:
      • Nucleus Ambiguus: Motor to larynx/pharynx (swallowing, phonation).
      • Dorsal Motor Nucleus: Parasympathetics to heart, lungs, GI.
      • Nucleus Solitarius: Visceral sensory (taste, baroreceptors).
  • Major Branches & Clinical Correlates:
    • Recurrent Laryngeal Nerve (RLN)
      • Function: Motor to most intrinsic laryngeal muscles.
      • Lesion: Hoarseness.
      • Vulnerable during: Thyroid surgery.
      • Course: Left RLN loops under aortic arch; Right RLN loops under right subclavian artery.
    • Superior Laryngeal Nerve (SLN)
      • Function: External branch innervates cricothyroid muscle (creates high-pitched sounds).
      • Lesion: Monotonous voice.
      • Vulnerable during: Ligation of superior thyroid artery in thyroidectomy.
  • Vagal Trunk Lesion (e.g., at jugular foramen):
    • Hoarseness (laryngeal muscle paralysis).
    • Dysphagia (pharyngeal muscle paralysis).
    • Uvula deviates AWAY from the side of the lesion.
  • Reflexes:
    • Gag Reflex: Afferent = CN IX, Efferent = CN X.
    • Baroreceptor Reflex: Aortic arch afferent and all parasympathetic efferent signals are carried by CN X.