• Innervation
    • Phrenic nerve
      • Roots: C3, C4, C5 (“C3, 4, 5 keeps the diaphragm alive”)
      • Provides motor innervation to the entire diaphragm.
      • Provides sensory innervation to the central part of the diaphragm (peritoneum and pleura).
    • Intercostal nerves (lower 6-7)
      • Provide sensory innervation to the peripheral diaphragm.
  • Structures Piercing the Diaphragm
    • Mnemonic: “I (IVC) 8 10 Eggs (Esophagus) At (Aorta) 12
    • T8 (Caval opening):
      • Inferior Vena Cava (IVC)
      • Right phrenic nerve branches
    • T10 (Esophageal hiatus):
    • T12 (Aortic hiatus):
      • Aorta
      • Thoracic duct
      • Azygos vein
  • Diaphragmatic Hernias
    • Hiatal Hernia
      • Sliding Hernia (Type 1): Most common (>95%). Gastroesophageal (GE) junction and stomach cardia slide upward into the thorax. Associated with GERD.
      • Paraesophageal Hernia (Type 2): Gastric fundus herniates into the thorax alongside the esophagus. GE junction remains in normal position. Risk of strangulation.
    • Congenital Diaphragmatic Hernia (CDH)
      • Bochdalek Hernia: Most common CDH (~95%). Defect is posterolateral, usually on the left. Abdominal contents herniate into the thorax, leading to pulmonary hypoplasia. Presents with respiratory distress in a newborn.
      • Morgagni Hernia: Rare. Defect is anteromedial.
  • Clinical Correlations
    • Paralysis of Hemidiaphragm:
      • Due to phrenic nerve injury (e.g., thoracic surgery, tumor compression).
      • On CXR, the affected hemidiaphragm is elevated.
      • On fluoroscopy (“sniff test”), there is paradoxical upward movement of the paralyzed side during inspiration.
    • Referred Pain (Kehr’s Sign):
      • Irritation of the diaphragmatic peritoneum (e.g., by blood from splenic rupture, subphrenic abscess, cholecystitis) can cause referred pain to the shoulder tip (C3-C5 dermatome).
    • Hiccups (Singultus):
      • Involuntary, spasmodic contraction of the diaphragm, causing sudden inhalation that is stopped by glottic closure.
      • Can be caused by phrenic nerve irritation.