| Main Cause |
Chronic HT, Diabetes, Aging |
Malignant HT |
Malignant HT, Vasculitis (immune) |
| Key Histology |
Homogeneous, pink, glassy thickening, narrow lumen |
"Onion-skin" layers, smooth muscle proliferation, very narrow lumen |
Eosinophilic fibrin, inflammation, "smudged" wall |
| Severity/Context |
Chronic damage (e.g., benign nephrosclerosis, lacunar infarcts) |
Acute, severe, rapid damage (malignant nephrosclerosis, hypertensive emergency) |
Acute, severe damage (e.g., malignant nephrosclerosis, active vasculitis) |
| Vessel Type |
Arterioles, small arteries |
Arterioles, small arteries |
Arterioles, capillaries, venules |
