High-Yield Management: CONTRAINDICATION to bag-valve-mask (BVM) ventilation/PPV via mask (dilates stomach/bowels in chest, worsening pulmonary hypoplasia/collapse).
Next Step: Immediate ET Intubation + Placement of Orogastric (OG) tube for decompression.
Meconium-Stained Amniotic Fluid
Management: Routine endotracheal suctioning at delivery is NO LONGER RECOMMENDED, regardless of infant vigor.
Follow standard algorithm: If depressed (apneic/hypotonic) → Initial steps under warmer → PPV if HR < 100 or non-breathing.
Maternal Opioid Exposure
Infant presents with respiratory depression secondary to maternal intrapartum opioid administration.
High-Yield Management: DO NOT give Naloxone (can precipitate acute withdrawal seizures in opioid-exposed infants).
Next Step: Provide ventilatory support via PPV until respiratory drive recovers.
Prematurity (<32 Weeks GA)
Management:
Place infant up to neck in polyethylene plastic wrap without drying skin (prevents evaporative heat loss).
Use thermal mattress.
Use CPAP instead of PPV if infant is breathing spontaneously with HR > 100 but has dyspnea/grunting.
Post-Resuscitation Care
Monitor for therapeutic hypothermia eligibility if moderate/severe Hypoxic-Ischemic Encephalopathy (HIE) present (gestation ≥35 weeks, initiate within 6 hours of birth).
Monitor blood glucose (risk of severe hypoglycemia).
Monitor arterial blood gas (ABG), electrolytes, and CXR (verify ETT placement 1–2 cm above carina).