Splenic rupture

Epidemiology & Risk Factors

  • Blunt abdominal trauma (e.g., MVC, falls, physical assault, direct blows) is the most common cause.
  • Spontaneous/Atraumatic rupture risk factors:
    • Infectious: EBV (Infectious mononucleosis), CMV, malaria. c
    • Hematologic malignancies: Leukemia, lymphoma.
    • Inflammatory/Autoimmune: Rheumatoid arthritis (Felty syndrome), SLE.
    • Other: Portal HTN, splenic amyloidosis, vascular abnormalities.
  • Anatomical risk: Splenomegaly from any etiology renders the spleen highly susceptible to trauma.

Clinical Features

  • History of blunt abdominal trauma or recent viral illness/fever.
  • LUQ abdominal pain.
  • Left shoulder pain (Kehr sign) due to blood/phrenic nerve irritation of the diaphragm.
  • Peritoneal signs (guarding, rigidity, rebound tenderness) if hemoperitoneum is present.
  • Hemodynamic instability / Hypovolemic shock:
    • Hypotension (BP < 90 mmHg).
    • Tachycardia (HR > 120 bpm).
    • Cold, clammy skin, diaphoresis.
    • Altered mental status.

Diagnosis

  • Initial/Screening:
    • Hemodynamically unstable patient: FAST (Focused Assessment with Sonography for Trauma) scan to look for free fluid (hemoperitoneum) in the RUQ, LUQ, pelvis, and pericardium.
    • Hemodynamically stable patient: Contrast-enhanced CT scan of the abdomen/pelvis (highly sensitive and specific; evaluates degree of injury and checks for contrast extravasation/“blush”).
  • Confirmatory/Gold Standard: Contrast-enhanced CT scan of the abdomen/pelvis (grades splenic injury from I to V).
  • Key Labs:
    • Serial Hgb/Hct (Note: May be normal initially in acute hemorrhage).
    • Type & Crossmatch (for immediate transfusion if needed).
    • Coagulation profile (PT/INR, PTT), platelet count, lactate.
  • Biopsy: Contraindicated due to extreme hemorrhage risk.

Management

  • Immediate Stabilization (ABCs):
    • Secure airway/breathing if compromised.
    • Establish two large-bore peripheral IVs (14G or 16G).
    • Aggressive fluid resuscitation with isotonic crystalloids.
    • Initiate 1:1:1 massive transfusion protocol (MTP: PRBCs, FFP, platelets) for hemorrhagic shock.
  • Hemodynamically Unstable Patient (with positive FAST or peritoneal signs):
    • Urgent exploratory laparotomy.
    • Splenectomy is standard in unstable patients to control life-threatening hemorrhage (partial splenectomy or splenorrhaphy preferred in children if stable enough).
  • Hemodynamically Stable Patient (or stabilized after initial fluid bolus):
    • Nonoperative Management (NOM) is the standard of care, regardless of injury grade (I–V), if stable:
      • Strict bed rest, intensive monitoring (ICU), serial abdominal exams, and serial Hgb monitoring.
      • Splenic artery embolization (SAE) / Angioembolization if CT shows contrast blush (extravasation) or if AAST grade is IV-V.
    • Failure of NOM (e.g., drop in Hgb, worsening tachycardia/hypotension, development of peritonitis) requires conversion to laparotomy.
  • Post-Splenectomy Care (Prophylaxis):
    • Patients undergoing splenectomy require vaccinations against encapsulated organisms:
      • Streptococcus pneumoniae
      • Neisseria meningitidis
      • Haemophilus influenzae type b (Hib)
    • Timing: Administer vaccinations ≥ 14 days postoperatively (to maximize immune response), or 14 days preoperatively for elective procedures.
    • Daily prophylactic oral penicillin (especially in children) and education to seek immediate care and empiric broad-spectrum antibiotics (e.g., amoxicillin-clavulanate) for any fever.

Complications

  • Overwhelming Post-Splenectomy Infection (OPSI): Life-threatening fulminant sepsis, primarily caused by S. pneumoniae. Risk is highest in children and in the first few years post-splenectomy.
  • Delayed Splenic Rupture: Hemorrhage occurring days to weeks after blunt trauma (often due to subcapsular hematoma expansion and rupture).
  • Reactive Thrombocytosis: Transient, benign increase in platelet count (peaks 1–2 weeks post-op); usually does not require treatment unless severe or risk factors for thrombosis exist.
  • Pancreatic Fistula / Tail Injury: Iatrogenic injury during splenectomy due to the close proximity of the pancreatic tail to the splenic hilum.
  • Left Pleural Effusion / Atelectasis: Postoperative reactive effusion or diaphragmatic splinting due to pain.