Epidemiology


Etiology


  • Primary Spontaneous Pneumothorax (PSP): Occurs without underlying lung disease. Classic patient is a tall, thin young male, often a smoker. Caused by rupture of apical subpleural blebs.
  • Secondary Spontaneous Pneumothorax (SSP): Occurs in patients with pre-existing lung disease. Most commonly associated with COPD; other causes include asthma, TB, cystic fibrosis, and interstitial lung disease.
  • Traumatic Pneumothorax: Caused by blunt or penetrating chest trauma (e.g., rib fracture).
  • Iatrogenic Pneumothorax: A subset of traumatic pneumothorax resulting from medical procedures like central line placement (especially subclavian), thoracentesis, lung biopsy, or positive-pressure ventilation (barotrauma).
  • Tension Pneumothorax: A life-threatening emergency where a one-way valve mechanism allows air to enter the pleural space but not exit. This leads to a progressive buildup of pressure.

Pathophysiology


  • Spontaneous pneumothorax: rupture of blebs and bullae → air moves into pleural space with increasing positive pressure → ipsilateral lung is compressed and collapses
  • Traumatic pneumothorax
    • Closed pneumothorax: air enters through a hole in the lung (e.g., following blunt trauma)
    • Open pneumothorax: air enters through a lesion in the chest wall (e.g., following penetrating trauma)
      • Air enters the pleural space on inspiration and leaks to the exterior on expiration.
      • Air shifts between the lungs.
  • Tension pneumothorax
    1. Disrupted visceral pleura, parietal pleura, or tracheobronchial tree
    2. One-way valve mechanism, in which air enters the pleural space on inspiration but cannot exit
    3. Progressive accumulation of air in the pleural space and increasing positive pressure within the chest
    4. Collapse of ipsilateral lung; compression of contralateral lung, trachea, heart, and superior vena cava; angulation of inferior vena cava
    5. Impaired respiratory function, reduced venous return to the heart
    6. Reduced cardiac output
    7. Hypoxia and hemodynamic instability

Clinical features


  • Common Symptoms: Sudden onset of sharp, pleuritic, unilateral chest pain and dyspnea.
  • Physical Exam Findings:
    • Decreased or absent breath sounds on the affected side.
    • Hyperresonance to percussion.
    • Decreased tactile fremitus.
    • Asymmetric chest expansion.
  • Tension Pneumothorax Specifics: A medical emergency characterized by the above findings plus hemodynamic instability.
    • Marked respiratory distress, tachycardia, and hypotension (obstructive shock).
    • Tracheal deviation to the contralateral (unaffected) side.
    • Jugular venous distention (JVD) due to compression of the superior vena cava, hypotension

Diagnostics


Treatment


  • Small, stable, asymptomatic PSP: Observation and supplemental O2 (100% oxygen helps accelerate resorption of the air).
  • Large or symptomatic pneumothorax:
    • Needle aspiration (thoracocentesis) can be used for stable PSP.
    • Chest tube placement (thoracostomy) is the definitive initial treatment for large, secondary, or traumatic pneumothoraces.
  • Tension Pneumothorax:
    1. Immediate needle decompression: A large-bore needle is inserted in the 2nd intercostal space at the midclavicular line (or 4th/5th intercostal space, anterior axillary line). This converts the tension pneumothorax into a simple pneumothorax.
    2. Chest tube placement: Must be done after needle decompression for definitive management.
  • Recurrent Pneumothorax: Surgical intervention (VATS) with pleurodesis (chemical or mechanical scarring of the pleura) or pleurectomy is often indicated to prevent future episodes.