Etiology


  • In an adult, the spinal cord terminates in a tapering fashion as the conus medullaris (T12-S4) at the L1-L2 vertebral level. The collection of spinal nerves below this point (eg, L3-S4) exit inferiorly through their respective intervertebral foramina and are referred to as the cauda equina (ie, horse’s tail).
  • It constitutes a surgical emergency as delayed treatment can lead to irreversible neurological damage, including paralysis and incontinence.
  • Most common cause: Massive central lumbar disc herniation, typically at L4/L5 or L5/S1.
  • Other causes: Spinal stenosis, tumors (metastatic or primary), trauma/fractures, spinal epidural abscess, or epidural hematoma.

Functions


  • Innervates the lower limb, perineum, and pelvic organs
  • Innervates the internal and external anal sphincter
  • Provides parasympathetic innervation to the bladder

Clinical features


  • “Red Flag” Symptoms: This constellation of symptoms is critical to recognize.
    • Saddle Anesthesia: Numbness in the perineum, buttocks, and inner thighs (S3-S5 dermatomes) is a classic and significant finding. A common history question is asking if it feels normal when wiping after a bowel movement.
    • Bowel/Bladder Dysfunction: This is a hallmark of CES. It typically begins with urinary retention (difficulty starting a stream, loss of sensation of fullness) and can progress to overflow incontinence. Fecal incontinence and loss of anal sphincter tone are also key features.
    • Bilateral Sciatica: Severe, progressive, bilateral leg pain, numbness, and weakness.
    • Lower Extremity Weakness: Presents as asymmetric, areflexic paraplegia (LMN signs).
  • Physical Exam:
    • LMN Signs: Hyporeflexia/areflexia (e.g., decreased or absent patellar and Achilles reflexes), decreased muscle tone, and potential muscle atrophy.
    • Sensory Deficit: Check for perianal and “saddle” distribution numbness.
    • Rectal Exam: Decreased or absent rectal tone is a critical finding.

Diagnosis

  • Clinical Suspicion: Diagnosis is suspected based on the characteristic history and physical exam findings. There should be a low threshold for investigation.
  • Imaging: Urgent MRI is the gold standard and is required to confirm the diagnosis and identify the cause of compression.
  • CT Myelogram can be used if MRI is contraindicated or unavailable.

Management

  • Surgical Emergency: Immediate hospital admission and neurosurgical consultation are required.
  • Treatment: Urgent surgical decompression (e.g., laminectomy) is the definitive treatment to relieve pressure on the nerve roots.
  • Timing: Surgery is ideally performed as soon as possible, with better outcomes generally seen if done within 24-48 hours of symptom onset.
  • Adjunctive Tx: High-dose corticosteroids may be used to reduce inflammation and swelling.

Key Associations/Complications

  • Prognosis: Even with prompt surgery, recovery is variable. Permanent deficits can include urinary/bowel incontinence, sexual dysfunction, chronic pain, and leg weakness.
  • CES-I vs. CES-R:
    • CES-I (Incomplete): Patient has altered urinary sensation but no established urinary retention. This has a better prognosis if operated on urgently.
    • CES-R (Retention): Patient has painless urinary retention and overflow incontinence. Prognosis is significantly worse.