The brachial plexus is organized by the mnemonic: Really Tired Drink Coffee Black (Roots, Trunks, Divisions, Cords, Branches).

Upper Trunk (C5-C6) Lesion — Erb-Duchenne Palsy

  • Etiology
    • Infant: Lateral traction on neck during delivery.
    • Adult: Trauma (e.g., fall on shoulder).
  • Nerves Damaged
    • Primarily affects Musculocutaneous, Axillary, and Suprascapular nerves.
  • Muscles Affected
    • Deltoid (abduction)
    • Supraspinatus (abduction)
    • Infraspinatus (external rotation)
    • Biceps brachii (flexion, supination)
  • Clinical Presentation
    • Arm hangs by the side, medially rotated, pronated forearm, extended elbow.
    • Loss of abduction, external rotation, and flexion/supination.
  • Classic Sign
    • “Waiter’s tip” or “Porter’s tip” hand.

Lower Trunk (C8-T1) Lesion — Klumpke Palsy

  • Etiology
    • Infant: Upward force on arm during delivery (e.g., grabbing arm).
    • Adult: Grabbing a tree branch to break a fall; Pancoast tumor; cervical rib.
  • Nerves Damaged
    • Primarily affects Ulnar and Median nerves (intrinsic hand muscles).
  • Muscles Affected
    • Intrinsic muscles of the hand (lumbricals, interossei).
  • Clinical Presentation
    • Paralysis of intrinsic hand muscles, leading to impaired wrist/finger flexion and finger abduction/adduction.
    • Sensory loss along medial aspect of forearm and hand.
  • Classic Sign
    • Total “Claw Hand” (MCP joints are extended, IP joints are flexed).
  • Associated Syndrome
    • If T1 root is involved, can disrupt sympathetic chain Horner’s Syndrome (Ptosis, Miosis, Anhidrosis).

Long Thoracic Nerve (C5, C6, C7) Lesion

  • Etiology
    • Axillary lymph node dissection (e.g., during mastectomy), stab wound, chest tube insertion.
  • Muscle Affected
    • Serratus Anterior. This muscle’s function is to anchor the scapula to the thoracic cage and protract the scapula.
  • Clinical Presentation
    • Inability to anchor scapula.
  • Classic Sign
    • “Winging of the scapula”, most prominent when the patient pushes against a wall.

Thoracic Outlet Syndrome

  • Etiology
    • Compression of the brachial plexus (most often the lower trunk) and/or subclavian vessels as they pass between the clavicle and first rib.
    • Often caused by a cervical rib or hypertrophy of anterior scalene muscle.
  • Clinical Presentation
    • Mimics Klumpke palsy: Atrophy of intrinsic hand muscles, pain/paresthesia in C8-T1 distribution.
    • Vascular compromise: Swelling, discoloration (ischemia) of the arm, weak radial pulse.
  • Diagnostics
    • Adson’s test: Loss of radial pulse when head is turned toward the affected side and held in inspiration.