• Treatment
    • Immunocompetent:
      • Supportive care (hydration).
      • Nitazoxanide (inhibits pyruvate:ferredoxin oxidoreductase).
    • Immunocompromised:
      • HAART (Antiretroviral therapy) to restore immune function is the most effective intervention.
      • Nitazoxanide (often ineffective without immune reconstitution).
      • Paromomycin or Spiramycin (sometimes used, variable efficacy).
      • Octreotide (for symptomatic diarrhea control).