Harvey's Garden

Amebiasis

1 min read

Epidemiology

Etiology

Pathophysiology

Clinical features

Diagnostics

Intestinal amebiasis

  • Microscopic identification of cysts or trophozoites in fresh stool
  • Colonoscopy with biopsy: flask-shaped ulcers

Treatment

  • Asymptomatic Cyst Passer: Intraluminal agent alone (Paromomycin or Iodoquinol).
  • Invasive Disease (Colitis or Liver Abscess):
    1. Systemic tissue agent: Metronidazole (or Tinidazole).
    2. Followed by intraluminal agent: Paromomycin (to eradicate cysts in the lumen and prevent recurrence/spread). t
  • Liver Abscess Management: Drainage is rarely indicated (respond well to medical Tx). Drain only if:
    • Large (>5-10 cm).
    • Imminent rupture.
    • No response to antibiotics after 5-7 days.
    • Left lobe abscess (risk of rupture into pericardium).

Graph View

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