Epidemiology

Etiology

Pathophysiology

• Chronic Th2 cell–mediated disorder triggered by food antigens
• Eosinophilic infiltration of the esophageal mucosa

Clinical features

• Dysphagia, food bolus impaction
• Symptoms can be worsened by ingestion of food containing allergens.
• Associated features: atopy (e.g., asthma, rhinitis, atopic dermatitis, alimentary allergies)

Diagnostics

Endoscopic findings

• Circumferential mucosal lesions (e.g., rings, corrugations), with possible esophageal trachealization (presence of multiple rings in the esophagus, which results in a furrowed or corrugated appearance similar to the trachea)
• Longitudinal furrows

Histopathologic findings

• Intraepithelial accumulation of eosinophils

Treatment

• First-line: Proton pump inhibitors (PPIs)