Epidemiology

Etiology

Pathophysiology

Clinical features

Diagnostics

Treatment

Sympathomimetics

• Agents
  • Phentermine/topiramate
  • Phentermine
  • Diethylpropion
• Appetite suppressants
• Contraindicated in patients with:
  • Cardiovascular disease
  • Uncontrolled hypertension

GLP-1 agonists

• Beneficial in patients with type 2 diabetes
• Increased risk of pancreatitis and gallbladder disease
• May delay gastric emptying, resulting in nausea and vomiting.

Opioid antagonists/norepinephrine-dopamine reuptake inhibitors

• Naltrexone/bupropion
• Appetite suppressants

Lipase inhibitors

• Orlistat
• Blocks lipase in the bowel, leading to fat malabsorption.
• No longer routinely recommended due to many adverse effects