Anabolic and Catabolic effects

• Anabolic

  • Meaning: “Building up” processes. Building complex molecules from simpler ones (requiring energy).
  • ANA- = Add/Ascent (building up)
  • NADPH: Used for Anabolic processes (Building up) and Redox defense.
    • Production: HMP Shunt (via G6PD).
    • Consumption:
      1. Synthesis: Fatty acids, Cholesterol, Nucleotides.
      2. Protection: Reducing Glutathione (prevents oxidative stress).
      3. Immune: Respiratory Burst (NADPH Oxidase) in neutrophils.

• Catabolic

  • Meaning: “Breaking down” processes. Breaking down molecules (releasing energy).
  • CATA- = Collapse/Crash (breaking down)
  • NADH: Used for Catabolic processes (Breaking down) to make ATP.
    • Production: Glycolysis, TCA Cycle, Fatty Acid $\beta$-oxidation.
    • Consumption: Electron Transport Chain (Complex I) to generate ATP, Anaerobic Glycolysis, Gluconeogenesis